Infertility Disease DataBase (IDDB) provides a versatile resource for genes, experiments and clinical records related with the infertility diseases, data in IDDB is annually updated and freely served for biologists and doctors interested in reproduction and infertility.
Broadly speaking, infertility is the inability of biologies to reproduce by natural means.
Narrowly speaking, infertility is the inability to conceive for at least one year after trying and having unprotected sex in humans.
An disease ontology of infertility is provided in IDDB.
Many genes and chromosome regions are related with infertility diseases of human. Release 2020 of IDDB contains 307 genes and 202 records of chromosome regions in total. The details of genes and regions, including pathogenic variants, clinical samples and infertility pathway maps, are also listed in IDDB.
Model organisms, such as mouse, nematode, fruit fly, zebrafish are essential experimental animals for infertility disease research. The research of infertility gene in model organism is of great help for investigating the orthologous gene in human.